Publications

Selected Publications

Transgene-Free Disease-Specific iPSC Generation from Fibroblasts and Peripheral Blood Mononuclear Cells.

Fidan K, Ebrahimi A, Çağlayan ÖH, Özçimen B, Önder TT. Methods Mol Biol. 2016;1353:215-31.


 Generation of integration-free induced pluripotent stem cells from a patient with Familial Mediterranean Fever (FMF).

Fidan K, Kavaklıoğlu G, Ebrahimi A, et al.  Stem Cell Res. 2015;15(3):694-6.


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Chromatin-modifying enzymes as modulators of reprogramming.

Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ.
Nature. (2012) Mar; 483(7391):598-602.
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New lessons learned from disease modeling with induced pluripotent stem cells.

Onder TT, Daley GQ.

Curr Opin Genet Dev. (2012) Oct; 22(5):500-8.

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Identification of selective inhibitors of cancer stem cells by high-throughput screening1-s2.0-S0092867409007818-gr2.

Gupta PB*, Onder TT*, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES.

Cell. 2009 Aug 21;138(4):645-59. *equal contribution

 

 

 


 

 

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Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.

Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA.

Cancer Res. 2008 May 15;68(10):3645-54.

For a full list, click here (Pubmed).


Other Publications

Das PP, Shao Z, Beyaz S, et al. Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity. Mol Cell. 2014;53(1):32-48.
Unternaehrer JJ, Zhao R, Kim K, et al. The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming. Stem cell reports. 2014;3(5):691-8.
Zhu J, Adli M, Zou JY, et al. Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell. 2013;152(3):642-54.
Shyh-Chang N, Locasale JW, Lyssiotis CA, et al. Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science. 2013;339(6116):222-6.
Rai P, Young JJ, Burton DGA, Giribaldi MG, Onder TT, Weinberg RA. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence. Oncogene. 2011;30(12):1489-96.
Onder TT, Daley GQ. microRNAs become macro players in somatic cell reprogramming. Genome Med. 2011;3(6):40.
Kuo T-C, Chen C-T, Baron D, et al. Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol. 2011;13(10):1214-23.
Kojima Y, Acar A, Eaton EN, et al. Autocrine TGF- and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci. 2010;107(46):20009-20014.
Taube JH, Herschkowitz JI, Komurov K, et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A. 2010;107(35):15449-54.
Loewer S, Cabili MN, Guttman M, et al. Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet. 2010;42(12):1113-1117.
Ma L, Young J, Prabhala H, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010;12(3):247-56.
Rai P, Onder TT, Young JJ, et al. Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc Natl Acad Sci U S A. 2009;106(1):169-74.
Scheel C, Onder T, Karnoub A, Weinberg RA. Adaptation versus selection: the origins of metastatic behavior. Cancer Res. 2007;67(24):11476-9.